somatostatin相关论文
The caudal forelimb area (CFA) of the mouse cortex is essential in many forelimb movements,and diverse types of GABAergi......
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The present study was performed to investigate the morphology and topographic distribution,developmental changes of Soma......
Somatostatin receptor-mediated suppression of GABAergic synaptic transmission in cultured rat retina
Somatostatin(SRIF)is widely distributed in the central nervous system,which may modulate neurotransmitter release via ac......
Is prophylactic somatostatin effective to prevent post-endoscopic retrograde cholangiopancreatograph
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目的:探索n 177Lu标记1，4，7-三氮杂环壬烷-1，4，7-三乙酸(NOTA)-n D-苯丙氨酸1-酪氨酸3-苏氨酸-8-奥曲肽(TATE)的最佳条件，评......
生长抑素又称生长激素释放抑制因子(SRIF)，是一种神经递质、神经调质和神经营养因子，通过激活5种特异的G蛋白偶联受体发挥作用。SRIF......
目的:探究高剂量生长抑素对急诊肝硬化合并食管胃底静脉曲张破裂出血的疗效增益价值.方法:将于2019年6月-2020年4月在本院接受治疗......
A Stress response pathway upregulates somatostatin level and transcription in pancreatic delta cells
Somatostatin secretion from islet delta-cells plays an important role in regulating islet function and is tightly co......
Immunohistochemical study on distribution of endocrine cells in gastrointestinal tract of flower fis
AIM: To detect distribution and relative frequency of endocrine cells in gastrointestinal tract of flower fish (Pseudoph......
多种肿瘤组织有生长抑素受体(somatostatin receptor,SSTR)的高表达.本实验通过SSTR的介导,以99mTc-Sandostatin(善得定)为标记物,......
Preserving GABAergic interneurons in acute brain slices of mice using the N-methyl-D-glucamine-based
Defects in the function and development of GABAergic interneurons have been linked to psychiatric disorders, so preserva......
To be or not to be:The host genetic factor and beyond in Helicobacter pylori mediated gastro-duodena
Helicobacter pylori(H.pylori)have long been associated with a spectrum of disease outcomes in the gastroduodenal system.......
Reduction in duodenal endocrine cells in irritable bowel syndrome is associated with stem cell abnor
AIM: To determine whether the decreased density of duodenal endocrine cells in irritable bowel syndrome(IBS) is associat......
The chemically synthesized somatostatin (ss) gene was fused in phase with the 3′-end ofhepatitis B virus surface antige......
1965年Pecile和Mtiller据实验推测下丘脑存在一种能抑制生长激素释放的物质。嗣后Krulich等指出这可能是一种肽类。直到1972年,Gu......
糖尿病是一常见病和多发病。虽然由于胰岛素的广泛应用,已使它的严重后果大为改观,但并没有解决糖尿病的慢性并发症对健康和生命......
近年来,有关消化道激素的研究取得很大进展。消化系及非消化系疾病时消化道本身的病理生理有很多变化。迄今,关于内分泌腺病变与......
促甲状腺激素释放激素(TRH)可作用于垂体前叶靶细胞的特异受体,激活腺苷酸环化酶—环磷酸腺苷系统,促进促甲状腺激素(TSH)的合成与......
Diabetic retinopathy(DR) has been classically considered to be a microcirculatory disease of the retina caused by the de......
Regenerative medicine,including cell-replacement strategies,may have an important role in the treatment of type 1 diabet......
目的探讨生长抑素与代谢综合征相关生化及抗氧化指标的关系。方法测定代谢综合征、代谢综合征高危人群以及正常人群的血清生长抑素......
Hypercalcemia Appeared in a Patient with Glucagonoma Treated with Octreotide Acetate Long-acting Rel
PABCREATIC neuroen docrine tumours are uncom-mon neoplasms of the pancreas.They may causea clinical syndrome due to horm......
Prolonged overproduction of growth hormone,like insulin-like growth factor-1 hypersecretion leads to acromegaly in adult......
生长抑素及其类似物(somatostatln analogue,SSA)具有抗肿瘤的作用,生长抑素受体显像技术就是应用有关的放射性核素标记SSA,将放射......
目的:探讨生长抑素受体亚型SSTR2和SSTR3在不同类型、不同部位淋巴瘤中的表达情况并分析其临床意义。方法:采用RT-PCR法检测105例4......
An improved glucose-DAB-nickel immunohistochemistry method and its application on protozoan Stylonyc
Using a modification of the very sensitive glucose-DAB-nickel(GDN)immunohistochemistry method,FOS(the expression protei......
Antiproliferative effect of octreotide on gastric cancer cells mediated by inhibition of Akt/PKB and
AIM:To investigate the antiproliferative effect of octreotide,a long-acting analogue of somatostatin,on gastric cancerc......
AIM:Somatostatin and its analogues may suppress thegrowth of various tumor cells.However,the effect ofoctreotide on gro......
OBJECTIVE: To evaluate the effect of tamoxifen (TAM) combined with a somatostatin analogue,octretide (OCT) on advanced ......
胰腺癌早期诊断困难,对化疗、放疗均不敏感。至今尚无理想的治疗措施。近年研究表明,生长抑素具有抗细胞增殖作用,并发现胰腺癌中......
AIM:To investigate whether octreotide can inhibit thegrowth of human gallbladder cancer cells in vitro and toelucidate ......
Effect of octreotide on human pancreatic cancer cells after transfected with somatostatin receptor t
AIM:To observe the effect of octreotide on apoptosis rateof human pancreatic cancer cells PC-3 after transfectedwith so......
AIM:To explore the difference of somatostatin receptorsubtype 2 (SST2R) gene expression in pancreatic canceroustissue a......
Antiangiogenic effect of somatostatin receptor subtype 2 on pancreatic cancer cell line:Inhibition o
AIM:To investigate the anti-angiogenic effect ofsomatostatin receptor subtype 2 (SSTR2) gene transfer intopancreatic ca......
AIM:To evaluate the diagnostic sensitivity and accuracy andthe cost-effectiveness of this technique in the detection of......
目的 研究人工合成的生长激素释放剂GHRP 6对体外培养的人垂体生长激素腺瘤细胞GH分泌影响 ,并分析其可能的临床意义。方法 用原......
Few clinical studies have demonstrated an anti-proliferative activity of somatostatin (SST) analogs in carcinoids. We re......
神经内分泌肿瘤(NEN)是起源于神经内分泌细胞或肽能神经元的一类肿瘤,可原发于全身多种脏器.NEN病理异质性大,患者预后差异大.常规......
目的观察慢病毒介导的神经元特异性生长抑素(somatostatin，SST)过表达对大鼠海马电点燃癫痫的抑制作用。方法成年Sprague-Dawley (S......
BACKGROUND: Previous research has revealed that somatostatin can induce epilepsy, and that the levels of neuropeptide Y ......
Infant guinea pig retina model of glutamate toxicity and intervention of basic fibroblast growth fac
Impaired vision with oligemic ophthalmopathy is a result of excitotoxicity caused by excitatory amino acids, resulting i......
Objective: To investigate the association of changes in G and D cells in the antral mucosa with the production of gastri......
神经内分泌肿瘤(NENs)是一组起源于肽能神经元和神经内分泌细胞、具有神经内分泌标记物和可以产生多肽激素的异质性肿瘤,其中胃肠......
目的观察硬化剂注射联合生长抑素治疗食管静脉曲张破裂出血的疗效、安全性及对预后的影响。方法选取义乌市中心医院2014年1月至201......
目的观察内镜检查联合药物治疗肝硬化食管胃底静脉曲张破裂出血的临床效果，为临床诊治提供参考。方法选取华中科技大学同济黄州医院......
目的 探讨慢性砷中毒对大鼠空肠P物质(sP)、生长抑素(SS)表达的影响及其与空肠形态结构变化的关系.方法 将45只清洁级SD大鼠按性别......
